Zidovudine : AIDS Medications Uses and Side Effects

Zidovudine Uses: Medical Applications and Benefits

Zidovudine is a formidable enemy of the relentless human immunodeficiency virus (HIV). This extraordinary medication, belonging to the select nucleoside reverse transcriptase inhibitors (NRTIs), is your shield against the storm.


Zidovudine doesn’t just halt the virus; it’s the unsung hero safeguarding the next generation. It’s the keeper that, when given to HIV-positive mothers, cuts the cords of transmission, protecting the innocent. While it won’t wave the banner of a cure, Zidovudine holds the line, reducing the odds of AIDS and the horrors of HIV-related ailments. When combined with safe practices and lifestyle changes, it’s the key to locking away the virus and making the world safer.

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What is the Best Way to Use this Medicine?

  • Forms: Capsule, tablet, syrup
  • Dosage: Adults: Twice a day; Infants/children: 2-3 times a day (6 weeks and younger, every 6 hours); Pregnant women: 5 times a day
  • Follow Directions: Carefully adhere to prescription instructions.
  • No DIY: Don’t exceed or reduce the dosage without a doctor’s guidance.
  • Persistent Use: Continue even if you feel well; it doesn’t cure but controls HIV.
  • Don’t Stop Suddenly: Consult your doctor before discontinuing.
  • Refill Early: Ensure a timely supply; gaps may complicate treatment.
  • Side Effects: Treatment might pause if serious side effects occur.
  • ZIDOVUDINE Side Effects: What to Know

    Common, Mild Effects

  • Stomach pain or cramps
  • Heartburn
  • Diarrhea (in children)
  • Constipation
  • Headache
  • Sleep difficulties
  • Serious Effects - Contact Your Doctor

  • Rash
  • Skin blistering or peeling
  • Hives
  • Itching
  • Breathing/swallowing trouble
  • Swelling of eyes, face, or throat
  • Remember to report any severe symptoms promptly.

    Special Precautions for ZIDOVUDINE Use


  • Inform your doctor if you’re allergic to zidovudine or its ingredients.
  • Medications

  • Share your current medications, including chemo drugs, with your doctor.
  • Dosing adjustments may be necessary.
  • Health Conditions

  • Report any history of kidney disease.
  • Pregnancy & Breastfeeding

  • Notify your doctor if you are pregnant or planning pregnancy.
  • Avoid breastfeeding if you have HIV or take zidovudine.
  • Body Changes

  • Be aware that body fat may decrease in the face, legs, and arms.
  • Immune System

  • As your immune system strengthens, expect potential reactions to existing infections.
  • New or worsening symptoms post-treatment need immediate reporting to your doctor.