Naltrexone Hydrochloride HCL Uses & Side Effects


Unlocking the power to break free from addiction, Naltrexone emerges as a beacon of hope. This prescription miracle is your steadfast ally on the road to recovery. It is well known for its function in treating drug and alcohol abuse.


It is the guardian of your well-being, standing guard at the gates of temptation. By skillfully blocking the mu-opioid receptor, Naltrexone slams the door on the euphoria of alcohol and opioids, offering a lifeline to those in need.

But it doesn’t stop there – this remarkable medication even directs a symphony within your body, rewiring the mechanisms that drive your cravings. Whether in its extended-release intramuscular form, Vivitrol or as trusty tablets, Naltrexone is here to break the chains and set you free.

Advantages of Naltrexone

  • Craving Crusher: Reduces cravings for alcohol, making sobriety more achievable.
  • Endorphin Blocker: Diminishes alcohol’s pleasurable effects by blocking endorphin receptors.
  • Dopamine Control: Indirectly decreases dopamine release, reducing the desire to drink.
  • Early Recovery Aid: This is especially helpful during the intense craving phase of early recovery.
  • Energy Saver: Frees up mental and physical energy for emotional processing and coping strategies.
  • What is the Best Way to Use this Medicine?

    Before you start:

  • Avoid opioids for 7-10 days before beginning Naltrexone to prevent withdrawal symptoms.
  • Taking Naltrexone Tablets:

  • Follow your doctor’s instructions.
  • Take one tablet daily by mouth.
  • Treatment duration varies but often lasts for three months or more.
  • Naltrexone Injection:

  • Administered by a healthcare professional monthly.
  • Don’t try to inject it yourself.
  • It lasts for a month once helped and can’t be removed.
  • Notify other healthcare providers of your Naltrexone use, as it can affect opioid-containing medicines.
  • Carry written information about your medication for emergencies.
  • Naltrexone Side Effects

    Serious Concerns:

  • Watch for mood changes, depression, and suicidal thoughts.
  • Be aware of symptoms like persistent sadness, social withdrawal, sleep changes, or self-harming thoughts.
  • Be cautious about pneumonia and seek medical help for symptoms like shortness of breath or persistent cough.
  • Be alert to severe allergic reactions such as skin rash, swelling, breathing difficulties, chest pain, or dizziness.
  • Common Side Effects:

  • Nausea (usually temporary).
  • Vomiting.
  • Sleepiness.
  • Anxiety.
  • Headache.
  • Restlessness.
  • Abdominal pain.
  • Joint and muscle discomfort.
  • Weakness.
  • Changes in heart rate.
  • Gastrointestinal issues.
  • Skin rash.
  • Sexual function changes.
  • Increased energy, sweating, and more.
  • Discuss any annoying or constant side effects with your healthcare provider. This isn’t an exhaustive list, so consult your doctor or pharmacist for more details. If you experience any severe side effects, contact your doctor promptly.

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    Special Precautions for Naltrexone

    Before Taking:

  • Mention allergies to Naltrexone, naloxone, opioids, or any meds.
  • Disclose opioid use, even from the past week.
  • Avoid opioids during Naltrexone treatment; it blocks their effects.
  • Inform future doctors of one-time Naltrexone treatment.
  • Medications and Health:

  • Discuss all medications, including herbal products.
  • Highlight disulfiram and thioridazine use.
  • Report any history of depression or kidney disease.
  • Notify if you are pregnant, planning, or breastfeeding.
  • Medical Procedures:

  • Alert healthcare providers about Naltrexone before any medical or dental procedures.
  • Carry medical ID for emergencies.
  • Mental Health:

  • Understand Naltrexone won’t reduce suicide risk.
  • Seek help for symptoms like sadness, anxiety, or suicidal thoughts.
  • Ensure your family knows when to seek medical assistance if needed.
  • Please Note: The above information is for knowledge purposes only. Please consult your healthcare provider for personalized medical advice.