Lamivudine: HIV/AIDS Prevention Dose & Side Effects

Lamivudine: Side Effects, Dosage, and Uses

Lamivudine, a beacon of progress in modern medicine, is a prescription wonder in the form of oral tablets and solutions. Its story unfolds through brand-name legends like Epivir and Epivir-HBV but also whispers through the affordable elegance of generic versions.


In the battle against HIV, lamivudine is the unsung hero that never fights alone, always part of a dynamic duo or ensemble cast of medications. Prepare to embark on a journey through the world of lamivudine, where science meets hope and lives are transformed.

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What is the Best Way to Use this Medicine?

  • Prescription Precision: Follow your doctor’s orders and consult medication guides.
  • Separate Goals: Don’t mix Epivir (HIV) with Epivir-HBV (hepatitis B) treatments.
  • Meal Flexibility: Lamivudine plays well with or without food.
  • Child’s Weight Matters: Children over 30 pounds prefer tablet form; liquid may be less effective.
  • Kid-Friendly: If a child struggles with tablets, consider breaking Epivir for them.
  • Accurate Measurement: Use the provided syringe or a proper dose-measuring device, not your kitchen spoon.
  • Brand Awareness: Ensure you have the right brand for your condition when refilling.
  • Frequent Check-Ins: Expect regular medical tests, especially if taking Lamivudine for HIV or hepatitis B.
  • Virus Vigilance: Notify your doctor of any new or worsening hepatitis symptoms.
  • Doctor’s Orders: Stick to your prescribed HIV medication regimen; consult your doctor before changing anything.
  • Proper Storage: Keep Lamivudine in a tightly closed bottle at room temperature, away from moisture and heat.
  • Hepatitis B Alert: If you’ve had hepatitis B, stay vigilant for potential reactivation even after Lamivudine use.
  • These concise pointers ensure you master the art of Lamivudine usage for your well-being.

    Dosage Guidelines at a Glance

    For HIV Infection (Lamivudine):

  • Adults (18+): 300 mg daily (150 mg twice or 300 mg once daily).
  • Children (3 months to 17 years): Weight-based, with specific doses provided.
  • Children (0-2 months): Dosage not established.
  • Special Considerations: Oral solution is available for those who can’t swallow tablets; kidney disease may require a lower dosage.
  • For Hepatitis B Infection (Epivir-HBV):

  • Adults (18+): 100 mg once daily.
  • Children (2-17 years): Weight-based, with a maximum of 100 mg daily.
  • Children (0-1 year): Dosage not established.
  • Special Considerations: Oral solution is available for those who can’t swallow tablets; kidney disease may require a lower dosage.
  • These pointers provide a quick reference for Lamivudine dosages in HIV and Hepatitis B treatment, catering to adults and children.

    LAMIVUDINE Side Effects: What to Know

    Immediate Attention Needed

  • Allergic Reaction: Look out for hives, breathing difficulties, or facial swelling; seek emergency help.
  • Potentially Serious Side Effects

  • Lactic Acidosis Signs: Unusual muscle pain, breathing trouble, stomach pain, vomiting, irregular heart rate, dizziness, coldness, weakness.
  • Pancreas Problems: Severe upper stomach pain, spreading to the back, nausea, vomiting, fast heart rate.
  • Liver Problems: Midsection swelling, upper right stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of skin/eyes).
  • Immune System Effects: Notify your doctor of any signs of new infections, difficulty in speaking/swallowing, balance or eye movement issues, neck/throat swelling, menstrual changes, or impotence.
  • Common Side Effects

  • Nausea, diarrhea.
  • Headache.
  • Fever, fatigue, general malaise.
  • Ear or nose/throat infections.
  • Ear infection (especially in children): Ear pain, trouble hearing, ear drainage, fussiness.
  • Special Precautions for LAMIVUDINE Use


  • Take with or without food.
  • Tablets can be cut or crushed; inquire about the solution form if needed.
  • Storage

  • Store tablets at 68-77°F (20-25°C).
  • Acceptable temperatures: 59-86°F (15-30°C).
  • Keep bottles tightly closed and avoid moist areas like bathrooms.
  • Refills

  • The prescription is refillable, with the number of refills indicated by your doctor.
  • Clinical Monitoring

  • Regular doctor appointments.
  • Periodic liver function and CD4 count blood tests.
  • Other required tests.
  • Availability

  • Check with your pharmacy for stock and partial dispensing.
  • Consider specialty or HIV pharmacies for convenience.
  • Prior Authorization

  • Many insurers require approval before covering the drug; your doctor will handle this process.
  • In these quick pointers, find essential Lamivudine use, storage, and access tips to ensure a seamless treatment journey.